Nitration of N-acetyl anilides using silver(I) nitrate/persulfate combination

Hathaichanok Sanjeam, Chutima Kuhakarn, Pawaret Leowanawat, Vichai Reutrakul, Darunee Soorukram* We reported nitration of N-acetyl anilides using a simple combination of AgNO3/K2S2O8. The advantages of the present procedure include the practical operation in an open-flask, considerably mild reaction conditions, and acceptable reaction time (6 h) without additional catalyst. Scale-up synthesis could also be performed in this study. Although both para- … Continue reading Nitration of N-acetyl anilides using silver(I) nitrate/persulfate combination